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Updated: Mar 13, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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グリセロール-3-リン酸脱水酵素によって触媒化された水素移転の内在的一次運動同位体への構造反応性効果

Archie C Reyes1, Tina L Amyes1, John P Richard1

  • 1Department of Chemistry, University at Buffalo, SUNY , Buffalo, New York 14260-3000, United States.

Journal of the American Chemical Society
|October 23, 2016
PubMed
まとめ

主要なデュテリウム運動同位体効果 (1°DKIE) は,グリセロール-3-フォスファート脱水素酶 (GPDH) での水素移転について研究された. これらの効果は酵素の反応性とは無関係であり,異なる活性化剤の間の類似した移行状態を示唆している.

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