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Updated: Mar 13, 2026

High-Pressure NMR Experiments for Detecting Protein Low-Lying Conformational States
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高圧 ZZ交換 NMR は,タンパク質の折り畳み移行状態の重要な特徴を明らかにする

Yi Zhang1, Soichiro Kitazawa2, Ivan Peran3

  • 1Department of Chemistry & Chemical Biology, Rensselaer Polytechnic Institute , Troy, New York 12180, United States.

Journal of the American Chemical Society
|October 27, 2016
PubMed
まとめ

ZZ交換 NMRと組み合わせた高圧で,タンパク質の急速な折り畳み速度を測定できます. この技術は,タンパク質ドメインの移行状態の洞察を明らかにし,タンパク質の折り畳みメカニズムを理解するのに役立ちます.

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