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Updated: Mar 13, 2026

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans
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Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans

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ポリグルトアミンの集積自由エネルギー風景が繰り返される

Mingchen Chen1, MinYeh Tsai1, Weihua Zheng1

  • 1Center for Theoretical Biological Physics, ‡Department of Bioengineering, and §Department of Chemistry, Rice University , Houston, Texas 77005, United States.

Journal of the American Chemical Society
|October 28, 2016
PubMed
まとめ

ポリグルタミン (polyQ) 繰り返しのタンパク質集積は,神経変性疾患と関連しています. この研究は,ポリQの繰り返しの長さがタンパク質の構造と結合にどのように影響し,疾患の重さにどのように影響するかを明らかにしています.

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