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Updated: Mar 12, 2026

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化学反応性を決定するためにタンパク質限定の近接を使用する

Tomonori Kobayashi1, Christian Hoppmann1, Bing Yang1

  • 1Department of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California, San Francisco , 555 Mission Bay Boulevard South, San Francisco, California 94158, United States.

Journal of the American Chemical Society
|November 1, 2016
PubMed
まとめ

この研究は,タンパク質の近接性を利用して,小分子とバイオ分子間の化学反応性を正確に予測する新しい方法を導入しています. この発見は,以前は不活性と考えられていたフッ素アセタミドが,システインチオールと密接に反応することを明らかにしています.

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