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Updated: Mar 12, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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LKB1の喪失は,セリン代謝とDNAメチル化と腫瘍発生を結びつける

Filippos Kottakis1,2,3, Brandon N Nicolay1,3, Ahlima Roumane1,2,3

  • 1Cancer Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, USA.

Nature
|November 4, 2016
PubMed
まとめ

LKB1腫瘍抑制剤の喪失は 代謝と表遺伝子を変化させることで 癌を助長します これは標的型療法に対する脆弱性を作り出し,LKB1変異がんに対する新しい治療戦略を提供します.

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