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Updated: Mar 12, 2026

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
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炎症 IKKβ- XBP1sの相互作用により,グルコースホメオスタシスを改善する

Junli Liu1, Dorina Ibi1, Koji Taniguchi2

  • 1Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02130, USA.

Cell
|November 5, 2016
PubMed
まとめ

IκBキナーゼβ (IKKβ) が関わる炎症は,肝臓のグルコースバランスを正常に調節する. 肥満マウスにおけるIKKβの増強は,ERのストレスを軽減することによって,インスリン感受性とグルコースホメオスタシスを改善した.

キーワード:
ERのストレスIKKβUPR についてXBP1s について糖尿病グルコース代謝炎症インスリン抵抗性肥満解き放たれたタンパク質反応

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