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Updated: Mar 12, 2026

Experimental Analysis of Apoptotic Thymocyte Engulfment by Macrophages
06:47

Experimental Analysis of Apoptotic Thymocyte Engulfment by Macrophages

Published on: May 24, 2019

7.8K

異なる組織ファゴサイトは,異なるホメオスタシスプログラムを指示するためにアポプトシス細胞をサンプルします.

Ryan J Cummings1,2, Gaetan Barbet1,2, Gerold Bongers1,2

  • 1Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

Nature
|November 10, 2016
PubMed
まとめ

デンドリット細胞とマクロファージを含むプロフェッショナルファゴサイトは,免疫耐性を維持するためにアポプトティック細胞をクリアします. この研究は 腸内の炎症や病気に影響を与える これらの細胞の 特殊な役割を明らかにしています

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Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
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