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Updated: Mar 12, 2026

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection
11:32

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection

Published on: December 4, 2010

15.9K

核孔複合細胞質mRNA輸出プラットフォームの構造と機能

Javier Fernandez-Martinez1, Seung Joong Kim2, Yi Shi3

  • 1Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA.

Cell
|November 15, 2016
PubMed
まとめ

mRNAの輸出に不可欠なNup82複合体は,新たに発見された分子構造を持っています. この構造は,効率的なエクスポートのために,核毛孔複合体 (NPC) 上に直接mRNAリモデリング因子を配置します.

キーワード:
Nup4 コンプレックスNup82複合体計算構造生物学クロスリンクと質量スペクトロメトリー電子顕微鏡統合構造の決定mRNAの輸出mRNPの改造核孔複合体小角X線散射

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Nuclear Export of mRNA02:31

Nuclear Export of mRNA

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NES are of three types- the canonical 10-residue long leucine-rich signal and other...
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Nuclear protein sorting is the selective trafficking of histones, polymerases, gene regulatory proteins into the nucleus and exporting RNAs and ribosomes to the cytosol. It is a tightly controlled process that regulates gene expression within a cell.
Proteins targeted to the nucleus carry nuclear localization signals or NLS recognized by import receptors in the cytosol. Similarly, proteins with nuclear export signals are recognized by export receptors. Import and export receptors are...
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