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Updated: Mar 12, 2026

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells
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造血幹細胞は数えて記憶する 自己再生分裂

Jeffrey M Bernitz1, Huen Suk Kim1, Ben MacArthur2

  • 1Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1496, New York, NY 10029, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1496, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1496, New York, NY 10029, USA.

Cell
|November 15, 2016
PubMed
まとめ

血液形成幹細胞 (HSC) は分裂を記憶し,4つの分裂後に長期的な再生能力が失われます. この細胞記憶は,HSCの老化と年齢関連の変化に影響します.

キーワード:
老化する細胞分裂のカウント細胞メモリ休眠状態造血幹細胞

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