冠動脈外科研究 (CASS) レジストリにおける無症状の左主冠動脈疾患
H A Taylor1, N J Deumite, B R Chaitman
1Department of Medicine, University of Alabama Medical Center, Birmingham 35294.
Circulation
|June 1, 1989
まとめ
左主冠動脈疾患の患者はほとんど無症状である. 外科治療は,医療管理と比較して,無症状の個体において生存率を大幅に改善します.
科学分野:
- 心臓病学 心臓病学
- 心血管外科手術についてです.
- クリニック・リサーチ 臨床研究
背景:
- 左主動脈冠動脈疾患 (LMCA) は,冠動脈血管検査を受ける患者の数多くに影響します.
- LMCA疾患の患者のわずかな割合は無症状であり,ユニークな臨床的課題を提示しています.
研究 の 目的:
- LMCA疾患の無症状患者の特徴を調査する.
- 症状のないLMCA疾患の患者における医療対外科管理の結果を比較する.
主な方法:
- 冠動脈外科手術研究 (CAS) レジストリからのデータの分析.
- 無症状および症状のあるLMCA疾患患者の臨床特徴と生存率の比較.
主要な成果:
- 無症状および症状のあるLMCA疾患の患者は,類似した狭窄症の重度,冠動脈疾患の程度,および左心室機能を示しました.
- 無症状のLMCA疾患に対する外科治療は,88%の5年生存率をもたらし,医療管理による57%の生存率 (p=0.02) よりも大幅に高かった.
結論:
- 症状のないLMCA疾患の患者は,症状のある患者と類似した疾患の重症度および心臓機能を共有しています.
- 外科的介入は,非外科的アプローチと比較して,無症状のLMCA疾患の長期生存率が優れている.
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