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Updated: Mar 11, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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Assays for Validating Histone Acetyltransferase Inhibitors

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自閉症スペクトル障害に関するヒストンアセチローム全体の関連研究

Wenjie Sun1, Jeremie Poschmann1, Ricardo Cruz-Herrera Del Rosario2

  • 1Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore.

Cell
|November 19, 2016
PubMed
まとめ

自閉症スペクトル障害 (ASD) は,さまざまな症例において共通のヒストンアセチル化シグネチャーを示し,共通の表遺伝的変化を明らかにします. このヒストンアセチローム全域関連研究 (HAWAS) は,ASDの潜在的な治療標的を特定しています.

キーワード:
自閉症スペクトル障害病原遺伝的変異エピジェネティクスヒストンのアセチル化ヒストンアセチル化定量特征ロシレギュロームプロファイリング

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