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Updated: Mar 11, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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ArfAとRF2による代替翻訳終了に関するメカニズム的洞察

Chengying Ma1, Daisuke Kurita2, Ningning Li3

  • 1Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Nature
|December 2, 2016
PubMed
まとめ

ノンストップメッセンジャーRNA (mRNA) に停滞したリボソームは,ArfA-RF2システムによって救出されます. このメカニズムは,リボソームのリサイクルを容易にするために,リリースファクター2 (RF2) を停止させるためのストップコドン代理としてArfAを使用します.

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