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Updated: Mar 10, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
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Published on: May 28, 2011

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スプライシングファクター1は,C. elegansにおける食事制限とTORC1経路の長寿を調節する

Caroline Heintz1, Thomas Koed Doktor2, Anne Lanjuin1

  • 1Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.

Nature
|December 6, 2016
PubMed
まとめ

RNAスプライシングホメオスタシスの維持は,老化するワームの寿命を予測します. 食事制限は,スプライシング因子1 (SFA-1) を調節することで,スプライシングを改善し,寿命を延ばし,スプライショーム調節が健康的な老化を促す可能性があることを示唆しています.

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