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Updated: Mar 10, 2026

Hypoxia Alters miRNAs Levels Involved in Non-Mendelian Inheritance of Autism Spectrum Disorder in Mice
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Hypoxia Alters miRNAs Levels Involved in Non-Mendelian Inheritance of Autism Spectrum Disorder in Mice

Published on: July 11, 2025

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自閉症における lncRNA,スプライシング,および地域的な遺伝子発現パターンの全ゲノム変化

Neelroop N Parikshak1,2, Vivek Swarup1,2, T Grant Belgard1,2

  • 1Center for Autism Research and Treatment and Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.

Nature
|December 6, 2016
PubMed
まとめ

自閉症スペクトル障害 (ASD) の遺伝的要因は共通の経路に収束する. この研究では,非コーディングRNAの調節不全,スプライシングの変化,ASDの脳における地域的な遺伝子発現の違いの減少が明らかになりました.

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