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Updated: Mar 10, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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オーソステルおよびアロステル抗薬によるCCキモカイン受容体2の構造

Yi Zheng1, Ling Qin1, Natalia V Ortiz Zacarías2

  • 1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.

Nature
|December 8, 2016
PubMed
まとめ

CCキモカイン受容体2 (CCR2) の構造に関する洞察は,新しい薬標的を明らかにする. この研究は,CCR2抗体複合体の構造を詳細に説明し,炎症性および神経変性疾患に対する治療法の開発のための新しい戦略を提供します.

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