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Updated: Mar 10, 2026

Chemical Triphosphorylation of Oligonucleotides
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Chemical Triphosphorylation of Oligonucleotides

Published on: June 2, 2022

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フォスフォラミド酸塩モルフォリノオリゴヌクレオチドとそのキメラの合成 フォスフォラミド酸塩化学

Sibasish Paul1, Marvin H Caruthers1

  • 1Department of Chemistry and Biochemistry, University of Colorado , Boulder, Colorado 80309, United States.

Journal of the American Chemical Society
|December 10, 2016
PubMed
まとめ

新しいフォスフォロダイアミド酸モルフォリノ (PMO) アナログとPMO-DNAキメラを合成した. いくつかの改変されたPMOは,RNaseH1の結合を強化し,活性化させ,オリゴヌクレオチドの研究を進めています.

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