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Updated: Mar 10, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

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B12-ラジカルSAM酵素PoyCは,ポリテオナミド生物合成中にバリンCβ-メチル化を触媒する

Aubérie Parent1, Alain Guillot1, Alhosna Benjdia1

  • 1Micalis Institute, ChemSyBio, INRA, AgroParisTech, Université Paris-Saclay , F-78350 Jouy-en-Josas, France.

Journal of the American Chemical Society
|December 10, 2016
PubMed
まとめ

研究者らは,PoyCをペプチドCβメチル化を行う最初のB12依存性S-アデノシルメチオニン酵素と特定した. この発見は,ポリテオナミド生物合成とB12根 S-アデノシルメチオニン酵素の理解を進めている.

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