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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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スピノール誘導体のリン酸触媒による非対称合成

Shaoyu Li1,2, Ji-Wei Zhang1, Xian-Lin Li1

  • 1Department of Chemistry, South University of Science and Technology of China , Shenzhen 518055, China.

Journal of the American Chemical Society
|December 10, 2016
PubMed
まとめ

研究者は,軸性キラル 1,1'-スピロビインドン-7,7'-ジオール (SPINOL) 誘導体のための新しいリン酸触媒非対称合成を開発した. この効率的な方法は,低触媒負荷でも,高収量とエナチオ選択性を持つ特権SPINOL構造へのアクセスを提供します.

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