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Updated: Mar 10, 2026

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota

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フォトアフィニティタンパク質-リガンドラベル方式によるサイクルアデノシン二酸化塩素結合タンパク質としてのグリセラルデヒド3酸塩脱水酵素の識別

Kehui Zhang1,2, Wei Sun2,3, Lihong Huang2

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University , Beijing 100191, China.

Journal of the American Chemical Society
|December 13, 2016
PubMed
まとめ

グリセラルデヒド3酸塩脱水酵素 (GAPDH) はサイクルアデノシン二酸化塩素 (cADPR) に結合し,そのカルシウム放出機能を媒介する. この研究では,GAPDHがcADPRとライアノジン受容体によるカルシウム動員との間の重要なリンクであると特定されています.

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