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Updated: Mar 10, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
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ジャヌス・ケレーターは,特殊なダイナミックレンジで生化学的に反応するMRIコントラストを可能にします

Eric M Gale1, Chloe M Jones1, Ian Ramsay1

  • 1The Athinoula A. Martinos Center for Biomedical Imaging, The Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School , 149 Thirteenth Street, Suite 2301, Charlestown, Massachusetts 02129, United States.

Journal of the American Chemical Society
|December 15, 2016
PubMed
まとめ

研究者は,マンガン (Mn) 基の新しいMRIコントラスト剤を"Janus"リガンドで開発しました. この薬剤は,生物学的信号に反応して,Mn3+とMn2+の酸化状態を切り替えることで,9倍のリラクシビティ変化を示します.

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