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Updated: Jan 6, 2026

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

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変調インターフェロメトリーによるトランスクリプションサイクルの単分子リアルタイム3Dイメージング

Guanshi Wang1, Jesse Hauver2, Zachary Thomas3

  • 1Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; BCMB Graduate Program, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.

Cell
|December 17, 2016
PubMed
まとめ

この研究では RNAポリメラーゼのような 分子機構を視覚化するための 新しい超高解像度画像技術が導入されました 遺伝子転写の過程で その動きと動態を正確に追跡し ゲノム調節に関する理解を深めています

キーワード:
RNAポリメラーゼ軸の位置づけホロ酵素インターフェロメトリ核孔複合体シグマ・ファクター単一分子超高解像度イメージングトランスクリプション転写サイクル

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