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Phase Transitions and Effect of Intermolecular Forces
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Aβ から派生したトリマーの安定化,組立,および毒性

Adam G Kreutzer1, Stan Yoo1, Ryan K Spencer1

  • 1Department of Chemistry, University of California, Irvine , Irvine, California 92697-2025, United States.

Journal of the American Chemical Society
|December 22, 2016
PubMed
まとめ

アルツハイマー病において重要な安定したβ-アミロイド (Aβ) トリマーが構造的に解明されました. これらのトリマーは 毒性の高いオリゴーマーに 自己組み立てられ 神経変性メカニズムに洞察を与えます

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