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Updated: Mar 9, 2026

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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単一の米国保健医療システム内の家族性高コレステロール血症の遺伝子識別

Noura S Abul-Husn1, Kandamurugu Manickam2, Laney K Jones2

  • 1Regeneron Genetics Center, Tarrytown, NY 10591, USA.

Science (New York, N.Y.)
|December 24, 2016
PubMed
まとめ

家族性高コレステロール血症 (FH) は診断不足ですが,ゲノムスクリーニングにより冠動脈疾患のリスクが高いキャリアが特定されます. 多くのFH患者は不十分な治療を受け,診断の改善と脂質低下治療の必要性を強調しています.

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