産業用バイオマニュファクチャリング:化学生産の未来

James M Clomburg¹, Anna M Crumbley¹, Ramon Gonzalez^2,3

¹Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX, USA.

Science (New York, N.Y.)

|January 7, 2017

まとめ

産業用バイオマニュファクチャリングは伝統的な化学生産の持続可能な代替手段ですこのアプローチは生物学的プロセスを活用して効率的で適応可能で分散された製造を行い現在の産業の課題に取り組んでいます

科学分野:

産業用バイオテクノロジー
化学工学
持続可能な製造

背景:

現在の産業化学製造は大規模なメガファシリテーションに依存し,環境,経済,物流の課題に直面しています.
これらの課題はエネルギー需要の高さ,資源密度,集中生産モデルから生じています

研究の目的:

伝統的な化学生産の持続可能な代替手段として,産業用バイオマニュファクチャリングの可能性を検討する.
生物学的プロセスが現在の製造戦略の限界に対処する方法を強調する.

主な方法:

産業用バイオ製造とその原則に関する既存の文献のレビュー.
バイオカタリシスや小規模な操作を含む生物学的プロセスの利点の分析
モデルシステムとして単炭素化合物の生物学的変換の探索.

主要な成果:

産業用バイオマニュファクチャリングは,単位数による経済を活用し,従来の単位スケールによる経済とは対照的です.
エンジニアリングされた生物触媒は,高い選択性,炭素とエネルギー効率,そして穏やかな条件下で調整可能な出力を可能にします.
バイオプロセスは本質的に資本効率が高く,拡張性があり,柔軟な生産を可能にします.

結論:

産業用バイオマニュファクチャリングはより持続可能で効率的で適応可能な化学製品へのパラダイムシフトをもたらします
このアプローチは分散された製造をサポートし,分散されたリソースへのアクセスと市場の反応性を可能にします.
単一炭素化合物の生物学的変換は,この新しい製造パラダイムを確立するための重要なテストベッドとして機能します.

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