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Updated: Mar 9, 2026

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ヒッポキナーゼLATS1と2は,ERαとのクロストークを通じてヒト乳房細胞の運命を制御する

Adrian Britschgi1, Stephan Duss1, Sungeun Kim2

  • 1Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland.

Nature
|January 10, 2017
PubMed
まとめ

大量の腫瘍抑制キナーゼ (LATS) 1と2は,エストロゲン受容体α (ERα) の安定性を制御することによって,乳房細胞の運命を調節する. LATSを消去すると,乳がんのリスクが増加する可能性があります.

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