霊長類における反省のための因果神経ネットワーク
Kentaro Miyamoto1, Takahiro Osada1,2, Rieko Setsuie1
1Department of Physiology, The University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
まとめ
最近の記憶と 遠い記憶を 監視する脳の領域が 明らかになったのです これらの領域を非活性化すると 記憶の信頼性判断が 選択的に損なわれ 記憶のリコールが 損なわれません
科学分野:
- 神経科学
- 認知神経科学
- 意思決定神経科学
背景:
- メタメモリー つまり 記憶状態の自己モニタリングは 戦略的な情報使用に不可欠です
- メタメモリーの基礎となる神経機構は,特に一時的に異なる記憶については,ほとんど知られていません.
研究 の 目的:
- メタメモリーの因果神経メカニズムを研究する
- 最近の記憶と 遠い記憶の 異なる脳領域を特定する
主な方法:
- 機能的磁気共鳴画像 (fMRI) がマカク類の全脳検査に使用された.
- 特定された脳の領域の因果的役割を評価するために,可逆不活性化技術が使用されました.
主要な成果:
- 前頭部領域9 (9/46d) で,遠隔イベントのメタメモリーのニューラル相関が発見されました.
- 最近の出来事の メタメモリーに 区分された領域は 領域6です
- これらの領域の不活性化により 認識能力に影響を及ぼさずに 選択的に認知判断が損なわれました
結論:
- メタメモリーストリームが平行に存在し,最近とリモートメモリーの認識ネットワークを監視しています.
- これらの発見は 異なる記憶の時間スケールにおける メタメモリーの神経基盤の 解離を強調しています
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