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Updated: Mar 8, 2026

Author Spotlight: Studying Macrophage-Epithelial Cell Interactions in Salivary Gland Regeneration After Injury
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DNA 損傷シグナリングは,粒子のポリプロイドマクロファージの運命を指示する

Laura Herrtwich1, Indrajit Nanda2, Konstantinos Evangelou3

  • 1Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

Cell
|January 14, 2017
PubMed
まとめ

持続的なトール型受容体2のシグナル伝達により,マクロファージは融合ではなく,DNA損傷反応によってポリプロイドになる. このプロセスは,慢性的な炎症の間,粒腫組織の再構築を形作ります.

キーワード:
DNA 損傷粒状腫炎症マクロファージミコバクテリア複製ストレス結核

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