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関連する概念動画

Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

4.0K
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
4.0K
Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

7.9K
Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
7.9K
Separation of Sister Chromatids02:17

Separation of Sister Chromatids

4.6K
At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
4.6K
Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

283.4K
In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
283.4K
Mitosis and Cytokinesis01:35

Mitosis and Cytokinesis

11.9K
In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
11.9K
The Phragmoplast01:59

The Phragmoplast

6.5K
Cell division is essential for organismal growth and development. In animal cells, the central spindle and its associated proteins form the midbody, a structure that has an essential role in cytokinesis. In plants, the central spindle, along with the microtubules, actin, and other cell components, matures into the phragmoplast, which is necessary for cytokinesis. Unlike the stationary midbody, the phragmoplast expands centrifugally, eventually leading to the formation of the new cell wall.
The...
6.5K

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関連する実験動画

Updated: Mar 8, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
10:38

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

16.7K

細胞 の 段階 分離 に つい て の 解明

Giulia Paci1, Edward A Lemke1

  • 1Structural and Computational Biology Unit and Cell Biology and Biophysics Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Cell
|January 14, 2017
PubMed
まとめ

研究者は細胞内のタンパク質相分離を 研究するための新しい光遺伝的ツールを開発しました この方法により,細胞の組織と病気のメカニズムを詳細に観察し,正確に制御することができます.

科学分野:

  • 細胞生物学
  • バイオ物理学
  • 分子生物学

背景:

  • タンパク質の相分離は 細胞の組織に不可欠です
  • 段階分離の調節不全は様々な病気に 関わっている.
  • 段階分離のダイナミクスを理解することは,細胞生物学にとって不可欠です.

研究 の 目的:

  • タンパク質の相分離を研究するための新しい光遺伝学的ツールを導入する.
  • 生物の細胞内の異なる相空間状態の評価を可能にする.
  • 高度な空間時間解像度でこれらのシステム間の移行経路を調査する.

主な方法:

  • 新しい光遺傳学的ツールの開発
  • 生きた細胞にこのツールを適用する.
  • 段階分離のダイナミクスを制御する.

主要な成果:

  • このツールは,異なるフェーズ・スペース体制の評価を可能にします.
  • 制度間の移行経路は研究することができます.
  • プロテイン相分離に対する前例のない空間時間的な制御が達成されました.

結論:

さらに関連する動画

Cell Co-culture Patterning Using Aqueous Two-phase Systems
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Cell Co-culture Patterning Using Aqueous Two-phase Systems

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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation

Published on: November 10, 2017

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関連する実験動画

Last Updated: Mar 8, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
10:38

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

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Cell Co-culture Patterning Using Aqueous Two-phase Systems
10:11

Cell Co-culture Patterning Using Aqueous Two-phase Systems

Published on: March 26, 2013

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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation

Published on: November 10, 2017

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  • タンパク質の相分離を研究するための強力な方法を提供します.
  • この技術は 細胞の組織と病気のメカニズムの 理解を進めるのです
  • 将来の研究では このツールを活用して 複雑な細胞過程を 調べることができます