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Updated: Mar 8, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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CBPへのRNA結合はヒストンのアセチル化と転写を刺激する

Daniel A Bose1, Greg Donahue1, Danny Reinberg2

  • 1Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell
|January 14, 2017
PubMed
まとめ

CBP/p300タンパク質は,強化RNA (eRNA) に直接結合する. この相互作用は活性増強剤の遺伝子発現とクロマチンの構造に影響を及ぼします.

キーワード:
CBP/p300 についてRNA結合アセチルトランスフェラーゼクロマチン改変エールナ強化剤エピジェネティック酵素遺伝子調節ヒストンのアセチル化非コーディングRNA

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