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Updated: Mar 8, 2026

Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1
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Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1

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ミトコンドリアのTCAサイクル酵素の核定位は,哺乳類のシゴティックゲノム活性化における重要なステップである

Raghavendra Nagaraj1, Mark S Sharpley1, Fangtao Chi1

  • 1Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Cell
|January 14, 2017
PubMed
まとめ

ミトコンドリアのトリカルボキシル酸 (TCA) サイクル酵素は,胚の発達初期に一時的に核に入り,エピジェネティックリモデリングとジゴティックゲノム活性化 (ZGA) に不可欠である. 核の局所化を制御し 胚の発達に影響を与えます

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