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Updated: Mar 8, 2026

Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR
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Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR

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挿入と削除はヒトがんにおける系統決定遺伝子を標的とする

Marcin Imielinski1, Guangwu Guo2, Matthew Meyerson3

  • 1Department of Pathology and Laboratory Medicine, Englander Institute for Precision Medicine, Institute for Computational Biomedicine, and Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA.

Cell
|January 17, 2017
PubMed
まとめ

癌細胞は 特定の機能に不可欠な遺伝子の 独特の変異パターンを表しています 研究者らは,様々ながんにおける分泌細胞系遺伝子の新しいインデルホットスポットを特定し,細胞タイプとがん発症の関連性を明らかにした.

キーワード:
発症したがん細胞ガンゲノミクスコード化しない遺伝的変異ソマティック変異過程統計的なドライバー発見変形地形全ゲノムシーケンシング

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