幼児の血管腫
Christine Léauté-Labrèze1, John I Harper2, Peter H Hoeger3
1Department of Dematology, Pellegrin Children's Hospital, Bordeaux, France.
Lancet (London, England)
|January 17, 2017
まとめ
乳児の良性腫瘍である乳児血栓腫は 治療なしで治る事が多い. 合併症を防ぐために,口服プロプラノロールによる早期介入が推奨されます.
科学分野:
- 小児腫瘍学
- 皮膚科
- 血管の異常
背景:
- 乳児の血液血管腫 (IHs) は,乳児における最も一般的な良性腫瘍であり,新生児の4. 5%に罹患する.
- IHは通常,人生の最初の数週間に急速に成長し,その後自発的に発現します.
- ほとんどのIHは治療を必要としませんが,いくつかのケースではリスクのために介入が必要になります.
研究 の 目的:
- 幼児の血管腫の管理について説明します.
- IHsの治療のための危険因子と指示を特定する.
- 早期プロプロノロール治療の役割を強調する.
主な方法:
- 幼児の血管腫の管理に関する現在の文献と臨床ガイドラインのレビュー.
- IHの増殖をモニタリングするための重要な時間点を特定する.
- 経口プロプロノロールの治療用薬および有効性の評価
主要な成果:
- IHの80%は3ヶ月までに最終的なサイズに達し,早期のフォローアップの必要性を強調しています.
- 治療の指示には,生命を脅かすIH,機能的リスク (視覚,栄養),潰瘍,美容的歪みが含まれます.
- 口服プロプラノロールはファーストラインの治療法であり,迅速な縮小を示し,最低6ヶ月の治療が必要です.
結論:
- 早期発見とモニタリングは,リスクのある幼児の血管腫を特定するために不可欠です.
- 口服プロプラノロールは,介入を必要とする内臓炎症に対する安全で効果的な第一線治療法です.
- プロプラノロールの治療を適時に開始すると,乳児の血管腫に関連する重篤な合併症を防ぐことができます.
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