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Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

2.0K
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
2.0K
Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

2.9K
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
2.9K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

2.0K
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
2.0K
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

641
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
641
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

635
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
635
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

761
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
761

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関連する実験動画

Updated: May 5, 2026

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
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Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Published on: May 15, 2011

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記事"心不全で入院した患者の間での挿入可能な心臓変圧器のカウンセリングと使用における性別と人種/民族の違い:ガイドライン-心不全プログラムからの発見"に関する手紙に対するヘスらによる回答

Paul L Hess1, Adrian F Hernandez1, Deepak L Bhatt1

  • 1From the Cardiology Section, VA Eastern Colorado Health Care System, Denver, CO (P.L.H.); Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO (P.L.H.); Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (A.F.H., A.S.H., E.D.P., P.J.S., S.M.A.-K.); Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA (D.L.B.); Department of Medicine, Northwestern University, Evanston, IL (C.W.Y.); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (L.H.S.); and Ahmanson-UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA (G.C.F.).

Circulation
|January 18, 2017
PubMed
まとめ

No abstract available in PubMed .

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Implantation of Total Artificial Heart in Congenital Heart Disease
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