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Updated: Mar 8, 2026

Label-Free Quantitative Proteomics Workflow for Discovery-Driven Host-Pathogen Interactions
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ホストプロテアゼを阻害する微生物から派生した反応性代謝物の発見

Chun-Jun Guo1, Fang-Yuan Chang2, Thomas P Wyche3

  • 1Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|January 24, 2017
PubMed
まとめ

腸内細菌はヒトのプロテアゼを阻害する 新しいピラジノン分子を産生します この発見は 合成生物学を用いて 主体生物学における 重要な微生物媒介体を明らかにしています

キーワード:
生物合成遺伝子クラスターメタゲノミクス微生物群自然産物ペプチドアルデヒドプロテアゼ阻害剤合成生物学

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