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Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters
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Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters

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種間オルガノゲネシスは,自律的な機能的小島を生成する.

Tomoyuki Yamaguchi1, Hideyuki Sato1, Megumi Kato-Itoh1

  • 1Division of Stem Cell Therapy, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.

Nature
|January 25, 2017
PubMed
まとめ

研究者はネズミの幹細胞から ネズミの大きさの臓を作りました 移植された小島は,糖尿病のマウスの血糖を1年以上正常化し,糖尿病治療に治療的可能性を示した.

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Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
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