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Updated: Mar 8, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

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2-アミノイミダゾール活性化核酸による非酵素RNA複製強化

Li Li1, Noam Prywes1, Chun Pong Tam1

  • 1Howard Hughes Medical Institute, Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.

Journal of the American Chemical Society
|January 25, 2017
PubMed
まとめ

研究者らは,2-アミノイミダゾールを用いて活性化ヌクレオチドを開発し,非酵素RNAの複製を著しく改善した. このブレークスルーはプライマーの拡張を加速し,生命の初期の研究のための混合配列RNAテンプレートの効率的な複製を可能にする.

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