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Updated: Mar 8, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Published on: March 24, 2017

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CcdA抗毒素タンパク質の乱れた領域内の隠された状態

Virginia M Burger, Alexandra Vandervelde1,2, Jelle Hendrix3,4

  • 1Structural Biology Brussels, Department of Biotechnology, Vrije Universiteit Brussel , B-1050 Brussels, Belgium.

Journal of the American Chemical Society
|January 27, 2017
PubMed
まとめ

バクテリアのCcdA抗毒素タンパク質は 細胞死を制御するために 乱れたC末端の腕を使います 新しいモデルは,これまで知られていなかった CcdA の状態を明らかにし,タンパク質の乱れが細胞の運命をどのように制御するかを示しています.

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Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography10:50

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Conserved Binding Sites

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Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
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Antibody Structure and Classes

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Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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