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AHR信号のフィードバック制御は腸の免疫を調節する

Chris Schiering1, Emma Wincent2, Amina Metidji1

  • 1The Francis Crick Institute, London, UK.

Nature
|February 2, 2017
PubMed
まとめ

過剰なCYP1A1酵素活性によるアリル炭化水素受容体 (AHR) のシグナル伝達が自然AHRリガンドを枯渇させ,腸内免疫を低下させる. AHRリガンドの摂取は,上皮細胞を強調して免疫機能を回復させる.

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