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臓がんにおけるメゼンキマサブ集団の合成的脆弱性

Giannicola Genovese1, Alessandro Carugo1,2,3, James Tepper1

  • 1Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

Nature
|February 9, 2017
PubMed
まとめ

臓がん細胞は,腫瘍性Kras信号を遮断し,Smarcb1- Mycネットワークを活性化することで攻撃的になります. タンパク質代謝とストレス反応をターゲットにすることで,臓管内腺がん (PDAC) のこの攻撃的行動が阻害される可能性があります.

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