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Updated: Mar 7, 2026

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SZT2はmTORC1信号のGATOR制御を指示する

Min Peng1, Na Yin1, Ming O Li1

  • 1Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

Nature
|February 16, 2017
PubMed
まとめ

発作値2 (SZT2) タンパク質は,mTORC1シグナル伝達を通じて栄養素を感知し,細胞成長を制御するために重要なGATOR1とGATOR2との複合体を形成します. SZT2欠乏症は,このプロセスを妨害し,マウスの細胞機能障害と新生児死亡を引き起こします.

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