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Updated: Mar 7, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
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オルトメトキシフェノールは,サイト選択性ヘテロバイ機能クロスリンクラーに適用できる便利な酸化バイオ結合反応剤である

Adel M ElSohly1, James I MacDonald1, Nina B Hentzen1,2

  • 1Department of Chemistry, University of California , Berkeley, California 94720-1460, United States.

Journal of the American Chemical Society
|February 17, 2017
PubMed
まとめ

研究者は,安定したo-メトキシフェノルを用いてタンパク質の生物結合体を生成する新しい方法を開発しました. このアプローチにより,がん研究のための複雑な生物分子の効率的な合成と 標的型配送システムを可能にします.

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