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Updated: Mar 7, 2026

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

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素早く調節されるアトロピソメールP,N-リガンドによって有効なエナントオセレクティブアルキン結合添加

Sourabh Mishra1, Ji Liu1, Aaron Aponick1

  • 1Center for Heterocyclic Compounds, Department of Chemistry, University of Florida , Gainesville, Florida 32611, United States.

Journal of the American Chemical Society
|February 17, 2017
PubMed
まとめ

新しいキラルバイアリルヘテロサイクリックリガンドであるMe-StackPhosは,メルドラムの酸受容体の銅触媒によるエナチオセレクティブ結合アルキニレーションを可能にします. この方法は,臨床前薬を含む有価なキラル構成要素を効率的に合成します.

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