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Updated: Mar 7, 2026

Detection of Detergent-sensitive Interactions Between Membrane Proteins
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Detection of Detergent-sensitive Interactions Between Membrane Proteins

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ER-プラズマ膜接触におけるTMEM24による脂質輸送は,パルス性のインスリン分泌を調節する

Joshua A Lees1, Mirko Messa1,2,3,4, Elizabeth Wen Sun1,2,3,4

  • 1Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520, USA.

Science (New York, N.Y.)
|February 18, 2017
PubMed
まとめ

トランスメブランタンパク質24 (TMEM24) は,ERと血の接触で脂質を補充し,インスリン分泌に不可欠なカルシウム信号を調整する. 2型糖尿病の重要な要因であるインスリン放出を阻害する.

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