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Studies of Chaperone-Cochaperone Interactions using Homogenous Bead-Based Assay
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HSP90 は 人間 の 遺伝子 変異 の 結果 に 影響 を 与える

Georgios I Karras1, Song Yi2, Nidhi Sahni2

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Cell
|February 21, 2017
PubMed
まとめ

熱ショックタンパク質90 (HSP90) は,変異タンパク質の機能を調節することによって,ヒトの遺伝疾患の重さに影響します. HSP90結合の増加は,より軽度の症状と相関し,疾患の変異性に関する洞察を提供します.

キーワード:
ファンコニ貧血HSP70 についてHSP90バッファリング癌について遺伝子と環境の相互作用

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