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Updated: Jan 7, 2026

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
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Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

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匂いの分子の化学的特徴から人間の嗅覚を予測する

Andreas Keller1, Richard C Gerkin2, Yuanfang Guan3

  • 1Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, NY 10065, USA.

Science (New York, N.Y.)
|February 22, 2017
PubMed
まとめ

分子の匂いを予測するのは 難しいことです DREAM 嗅覚予測チャレンジで開発された 機械学習モデルは 化学物質の特徴から 匂いの強度や愉しさを正確に予測できます

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
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The olfactory...
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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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