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Updated: Nov 11, 2025

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CRISPR/Cas9でTRACロカスにCARを標的にすると,腫瘍の拒絶が強化される

Justin Eyquem1, Jorge Mansilla-Soto1, Theodoros Giavridis1

  • 1Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, New York, New York 10065, USA.

Nature
|February 23, 2017
PubMed
まとめ

CRISPR/Cas9のゲノム編集により,キメリック抗原受容体 (CARs) がTRACロカスに正確に伝達され,T細胞の効能が向上し,B細胞の悪性腫瘍のアウトカムが改善されます.

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