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Updated: Mar 7, 2026

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells
08:38

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells

Published on: March 3, 2015

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古代ゲメット融合タンパク質 HAP2 は,ユカリオットII級融合タンパク質である

Juliette Fédry1, Yanjie Liu2, Gérard Péhau-Arnaudet3

  • 1Unité de Virologie Structurale, Institut Pasteur, 25-28 Rue du Docteur Roux, 75724 Paris, France; CNRS UMR 3569, 25-28 Rue du Docteur Roux, 75724 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Institut Pasteur, Rue du Docteur Roux, 75015 Paris, France; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany.

Cell
|February 25, 2017
PubMed
まとめ

HAP2タンパク質は,多くの真核生物におけるゲメットの融合に不可欠であり,ウイルスの融合タンパク質と似ています. この発見は マラリアの寄生虫の伝染を阻止する 戦略を提示しています

キーワード:
クラミドモナス・ラインハーティHAP2 についてクラスII融合タンパク質クリスタル構造ゲメット融合脂質挿入膜融合性繁殖感染を阻害するマラリアワクチンウイルスの侵入

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