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Updated: Mar 7, 2026

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
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マイクロRNA-210の小分子阻害は,腫瘍性低毒性回路を再プログラムする

Matthew G Costales1, Christopher L Haga1, Sai Pradeep Velagapudi1

  • 1Department of Chemistry, ‡Department of Molecular Therapeutics, and §Department of Neuroscience, The Scripps Research Institute , 130 Scripps Way, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|February 28, 2017
PubMed
まとめ

新しい小分子であるTargapremir-210は,マイクロRNA-210 (miR-210) の前駆者を選択的に標的にします. これは癌細胞の増殖を抑制し,特に低酸素の三重陰性乳がんではアポトーシスを引き起こす.

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