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Updated: Mar 7, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
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The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli

Published on: January 13, 2013

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ドメイン標的メタボロミクスは,コリバクチン生物合成のヘテロサイクルの組み立てステップを図示する

Eric P Trautman1,2, Alan R Healy1,2, Emilee E Shine2,3

  • 1Department of Chemistry, Yale University , New Haven, Connecticut 06520, United States.

Journal of the American Chemical Society
|February 28, 2017
PubMed
まとめ

ポリケチド合成酵素 (PKS) と非リボソームペプチド合成酵素 (NRPS) を研究するために,ドメイン標的メタボロミクスを開発しました. この方法は,E. coliにおけるコリバクチンの生成のような小分子生物合成における個々のドメイン機能を明らかにする.

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Functional Complementation Analysis FCA: A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways09:27

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