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Updated: Mar 6, 2026

Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment
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癌細胞におけるダウンレギュレーションを標的とする酵素指示による組み立てと分解プロセス

Zhaoqianqi Feng1, Huaimin Wang1, Rong Zhou1

  • 1Department of Chemistry, Brandeis University , 415 South Street, Waltham, Massachusetts 02454, United States.

Journal of the American Chemical Society
|March 4, 2017
PubMed
まとめ

この研究は,がん細胞の機能喪失を標的とした新しい化学療法戦略を導入しています. 酵素指示によるペプチド前駆体の組み立てと分解は,ダウンレギュレーションされた酵素を利用して,選択的に癌細胞を抑制します.

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